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Penicillin G procaine | C29H40N4O7S - PubChem

Penicillin G Procaine is the procaine salt form of penicillin G, a broad-spectrum, beta-lactam, naturally occurring penicillin antibiotic with antibacterial activity. Penicillin G binds to and inactivates the penicillin binding proteins (PBPs) located inside the bacterial cell wall.

Molecular Formula: C29H40N4O7S

PENICILLIN G PROCAINE (penicillin G procaine) | Pfizer ...

Penicillin G procaine is indicated in the treatment of moderately severe infections in both adults and pediatric patients due to penicillin-G-susceptible microorganisms that are susceptible to the low and persistent serum levels common to this particular dosage form in the indications listed below.

Penicillin G Procaine - FDA prescribing information, side ...

Apr 26, 1948 · Penicillin G Procaine is an equimolecular compound of procaine and penicillin G, administered intramuscularly as a suspension. It dissolves slowly at the site of injection, giving a plateau type of blood level at about 4 hours which falls slowly over a period of the next 15 to 20 hours. Approximately 60% of penicillin G is bound to serum protein.

Estimated Reading Time: 8 mins

PENICILLIN G PROCAINE Dosage and Administration | Pfizer ...

Penicillin G procaine (aqueous) is for intramuscular injection only. Administer by DEEP INTRAMUSCULAR INJECTION in the upper, outer quadrant of the buttock (dorsogluteal) or the ventrogluteal site. In neonates, infants and small children, the midlateral aspect of the thigh may be preferable. When doses are repeated, vary the injection site.

Bicillin C-R (penicillin G benzathine and penicillin G ...

Penicillin G procaine, (2. S,5. R,6. R)-3,3-Dimethyl-7-oxo-6-(2-phenylacetamido)-4-thia-1­ azabicyclo[3.2.0]heptane-2-carboxylic acid compound with 2-(diethylamino)ethyl p­ aminobenzoate (1:1)...

File Size: 657KB

Penicillin G procaine dosing, indications, interactions ...

Moderate/severe respiratory tracts infection caused by pneumococci (use aqueous penicillin G for acute stage of severe pneumonia, empyema, bacteremia, pericarditis, meningitis, peritonitis, or...

Penicillin G Procaine (Penicilling Procaine Injection ...

Nov 17, 2017 · Penicillin G procaine is chemically designated as (2S, 5R, 6R)-3,3-Dimethyl-7-oxo-6- (2-phenylacetamido)-4-thia-1- azabicyclo [3.2.0]heptane-2-carboxylic acid compound with 2- (diethylamino)ethyl p-aminobenzoate (1:1) monohydrate. Its molecular formula is C 16 H 18 N 2 O 4 S•C 13 H 20 N 2 O 2 •H 2 O with a molecular weight of 588.72.

Penicillin G Procaine and Penicillin G Procaine for ...

Penicillin G Procaine for Injectable Suspensionis a sterile mixture of Penicillin G Procaine andone or more suitable buffers, dispersants, or sus-pending agents, and preservatives. It containsnot less than 90.0 percent and not more than115.0 percent of the labeled amount of penicillinG, the labeled amount being not less than300,000 Penicillin G Units per container or permL of constituted Suspension.

Procaine Penicillin G (Canada) for Animal Use - Drugs

Jun 28, 2021 · Procaine Penicillin G is indicated for the parenteral treatment of infections caused by organisms susceptible to penicillin. Cattle & Calves: For the treatment of shipping fever syndrome, wound infections, navel infections, foot rot, bacterial infections associated with pneumonia, as well as for bronchitis and tracheitis when caused by or associated with penicillin susceptible organisms.

Fax: 204-943-9612

Penicillin G Benzathine and Penicillin G Procaine ...

Penicillin G benzathine and penicillin G procaine injection is in a class of medications called penicillins. It works by killing bacteria that cause infections. Antibiotics such as penicillin G benzathine and penicillin G procaine injection will not work for colds, flu, or other viral infections.

Penicillin G Procaine Intramuscular: Uses, Side Effects ...

This medication is used to treat a wide variety of bacterial infections. This medication is known as a long-acting natural penicillin antibiotic. It works by stopping the growth of bacteria.This...

Procaine penicillin G | CAS#:54-35-3 | Chemsrc

Feb 05, 2021 · Procaine penicillin G. CAS Number. 54-35-3. Molecular Weight. 570.700. Density. 1.1335 (rough estimate) Boiling Point. 663.3ºC at 760 mmHg.

1.1335 (rough estimate): 663.3ºC at 760 mmHg

Procaine Penicillin G Shortage CDC

Apr 17, 2017 · Penicillin G procaine is one of the recommended treatments for congenital syphilis and an alternative treatment for both neurosyphilis (NS) and ocular syphilis (OS). Pfizer, the sole manufacturer of Penicillin G procaine in the United States, continues to experience a manufacturing delay of this products.

Procaine and Benzathine Penicillin | Medcrine

Procaine Penicillin G injection is indicated for strains of bacteria that cause septicemia, empyema, pneumonia, endocarditis, and pericarditis. Benzathine penicillin, on the other hand, is indicated for the treatment of infections that are sensitive to low and prolonged serum penicillin levels such as syphilis, yaws , rheumatic fever , upper ...

DailyMed - PENICILLIN- penicillin g procaine injection ...

Feb 15, 2019 · ACTIONS: Penicillin G is an effective bactericide in the treatment of infections caused primarily by penicillin-sensitive organisms, such as Streptococcus equi and …

DailyMed - QUARTERMASTER- penicillin g procaine and ...

Jun 30, 2021 · Each 10 mL disposable syringe contains 1,000,000 units of Procaine Penicillin G, micronized, and 1 gram of Dihydrostreptomycin base, as Dihydrostreptomycin Sulfate, in an extended action base consisting of 1% w/v Hydrogenated Peanut Oil, 3% w/v Aluminum Monostearate, and Peanut Oil, q.s. Manufactured by a non-sterilizing process.

Procaine Benzylpenicillin - an overview | ScienceDirect Topics

Procaine penicillin G is a combination of benzylpenicillin with the local anaesthetic agent procaine. It is slowly absorbed after IM administration and hydrolysed to benzylpenicillin and thus used to achieve prolonged but low concentrations of benzylpenicillin. The combination seeks to reduce the pain and discomfort associated with a large IM ...

BENZYLPENICILLIN PROCAINE = PENICILLIN G PROCAINE ...

Remarks. – Also comes in 1 MIU and 3 MIU vials of powder for injection. – Do not confuse procaine benzylpenicillin with short-acting benzylpenicillin (penicillin G), administered several times per day by IV route. – Do not mix with other drugs in the same syringe. …

penicillin G benzathine and penicillin G procaine ...

Penicillin G benzathine and penicillin G procaine is a combination slow-onset antibiotic that is used to treat many types of severe infections caused by bacteria, including strep infections, pneumonia, and scarlet fever. Penicillin G benzathine and penicillin G procaine may also be used for purposes not listed in this medication guide.

Penicillin G Procaine - DrugFuture

Content of Penicillin G and procaine— Mobile phase— Dissolve 14 g of monobasic potassium phosphate and 6.5 g of tetrabutylammonium hydroxide solution (4 in 10) in about 700 mL of water, adjust with 1 N potassium hydroxide to a pH of 7.0, dilute with water to 1000 mL, and mix.

PENICILLIN G (Veterinary—Systemic)

Penicillin G is indicated in the treatment of Clostridium tetani in conjunction with tetanus antitoxin and supportive therapy. {R-6} Regulatory Considerations U.S.— Administration of penicillin G procaine to animals may produce procaine concentrations in the blood and urine that violate equine and greyhound racing commission prohibitions. {R-91; 92}

File Size: 320KB

Penicillin G Procaine 300,000 - GoatWorld.Com

Penicillin G Procaine Injectable Suspension should be stored in a cold room at a temperature between 2 o and 8 o C (36 o - 46 o F). Avoid freezing the product. HOW SUPPLIED: Penicillin G Procaine Injectable Suspension is supplied in 100-mL, 250-mL and 500-mL multiple-dose vials. NADA #65-505, Approved by FDA Manufactured by: Anthony Products Co.

Penicillin G Procaine; Third Edition: Blokdijk, G.J ...

'Penicillin G Procaine; Third Edition' presents readers with a whole new set of 722 pivotal questions to discuss your situation with your healthcare provider, consider your options, and help you make decisions that are right for you.

Author: G.J. Blokdijk

PENICILLIN G BENZATHINE/PENICILLIN G PROCAINE - …

Consumer information about the medication PENICILLIN G BENZATHINE/PENICILLIN G PROCAINE - INJECTION (Bicillin C-R), includes side effects, drug interactions, recommended dosages, and storage information. Read more about the prescription drug PENICILLIN G BENZATHINE/PENICILLIN G PROCAINE - INJECTION.

Penicillins - Pharmacology - Merck Veterinary Manual

Penicillin G and its oral congeners (eg, penicillin V) are active against both aerobic and anaerobic gram-positive bacteria and, with a few exceptions (Haemophilus and Neisseria spp and strains of Bacteroides other than B fragilis), are inactive against gram-negative organisms at usual concentrations.

Bicillin CR (Penicillin G Benzathine and Penicillin G ...

Sep 06, 2019 · Penicillin G procaine, (2S,5R,6R)-3,3-Dimethyl-7-oxo-6-(2-phenylacetamido)-4-thia-1- azabicyclo[3.2.0]heptane-2-carboxylic acid compound with 2-(diethylamino)ethyl paminobenzoate (1:1) monohydrate, is an equimolar salt of procaine and penicillin G. It occurs as white crystals or a white, microcrystalline powder and is slightly soluble in water.

Procaine Penicillin Price, 2021 Procaine Penicillin Price ...

Procaine Penicillin Price - Select 2021 high quality Procaine Penicillin Price products in best price from certified Chinese Penicillin G Procaine manufacturers, Oxytetracycline Injection suppliers, wholesalers and factory on Made-in-China

Why does Penicillin concentration is given in Units and ...

T max is 4 h (procaine IM). Penicillin G–sensitive is highly sensitive to microorganisms that are susceptible to the low and very prolonged serum levels common to this dose form in man.

Estimated Reading Time: 8 mins

Questions and Answers for Consumers on Penicillin G Procaine

Penicillin G procaine is an antibiotic that is given by injection into a muscle. It is approved to treat bacterial infections in many different parts of the body. It does not work to treat viral ...

PENICILLIN G PROCAINE | pfpfizeruscom

This product information is intended only for residents of the United States. for Health Care Professionals: PENICILLIN G Procaine Injectable Suspension U.S. Physician Prescribing Information. PENICILLIN-G-PROCAINE U.S. Medical Information Page - clinical & safety information, ways to contact Pfizer …

DailyMed - QUARTERMASTER- penicillin g procaine and ...

Jun 30, 2021 · Each 10 mL disposable syringe contains 1,000,000 units of Procaine Penicillin G, micronized, and 1 gram of Dihydrostreptomycin base, as Dihydrostreptomycin Sulfate, in an extended action base consisting of 1% w/v Hydrogenated Peanut Oil, 3% w/v Aluminum Monostearate, and Peanut Oil, q.s. Manufactured by a non-sterilizing process.

Using Injectable Penicillin G Procaine

benzathine and potassium penicillin. Penicillin G procaine has approved uses in dairy animals, as well as other animals, and is the most commonly used and available formulation for farm animals. Penicillin benzathine, which is combined with penicillin G procaine, is intended for use in beef cattle only.

penicillin G benzathine/penicillin G procaine - PDR

Penicillin G benzathine; penicillin G procaine is a combination of 2 long acting forms of penicillin G, a beta-lactam antibiotic. After slow release from an intermuscular injection, penicillin G benzathine and penicillin G procaine are hydrolyzed to penicillin G.

Procaine Penicillin G + Dihydrostreptomycin Sulfate ...

Procaine penicillin G and dihydrostreptomycin sulfate injection shouldn’t be administered if any hypersensitivity is discovered. Warnings. Special consideration should be taken for animals having kidney diseases or defective renal function. Do not exceed the recommended dosage or duration of treatment.

DailyMed - BICILLIN CR- penicillin g benzathine and ...

General. Penicillin G benzathine and penicillin G procaine have a low solubility and, thus, the drugs are slowly released from intramuscular injection sites. The drugs are hydrolyzed to penicillin G. This combination of hydrolysis and slow absorption results in blood serum levels much lower but more prolonged than other parenteral penicillins.

Procaine benzylpenicillin European Pharmacopoeia (EP ...

Procaine benzylpenicillin European Pharmacopoeia (EP) Reference Standard; CAS Number: 6130-64-9; Synonyms: Penicillin G procaine salt monohydrate; find -P3090000 MSDS, related peer-reviewed papers, technical documents, similar products & more at Sigma-Aldrich

Penicillin G Procaine - Manfaat, dosis dan efek samping ...

Apr 23, 2021 · Penicillin G procaine atau procaine benzylpenicillin adalah obat antibiotik untuk menangani infeksi bakteri, seperti anthrax, sifilis, atau infeksi Streptococcus beta-hemolitik grup A, atau infeksi Staphylococcus.. Penicillin G procaine bekerja dengan cara menghambat pembentukan dinding sel bakteri penyebab infeksi. Perlu diingat, obat ini tidak bisa infeksi akibat virus, seperti flu.

Penicillin G for Chickens and Ducks - PoultryDVM

Penicillin G sodium and potassium powder for injection can be stored at room tempera­ture (15-30°C). After reconstituting, the injectable solution is stable for 7 days when kept refrigerated (2-8°C) and for 24 hours at room temperature. Penicillin G procaine should be stored at 2-8°C; avoid freezing.

Bicillin CR (Penicillin G Benzathine and Penicillin G ...

Sep 06, 2019 · DESCRIPTION. Bicillin C-R (penicillin G benzathine and penicillin G procaine injectable suspension) contains equal amounts of the benzathine and procaine salts of penicillin G.It is available for deep intramuscular injection. Penicillin G benzathine is prepared by the reaction of dibenzylethylene diamine with two molecules of penicillin G.

Penicillin G Procaine + Dihydrostreptomycin Sulfate ...

Penicillin G procaine is an antibiotic that works by interfering with the formation of the bacteria’s cell wall during its growth. This weakens the cell wall and kills the bacteria. Dihydrostreptomycin sulfate is a semi-synthetic aminoglycoside antibiotic. It inhibits protein synthesis by …

Intramuscular treatment of subclinical staphylococcal ...

After four daily, treatments with procaine penicillin G and penethamate hydriodide, infections were eliminated from 56.5% and 68.8%, respectively, of quarters infected with penicillin G-sensitive staphylococci, and from 14.3% and 7.7%, respectively, of quarters infected with penicillin G …

Penicillin G Procaine (penicillin G procaine) dose ...

Procaine penicillin G is administered by intramuscular injection. Approximately 60% of penicillin G is bound to albumin. Penicillin G is rapidly eliminated via renal tubular excretion. A dose of 300,000 units of penicillin G procaine contains 120 mg of procaine.

Penicillin G Benzathine & Procaine Injection l Injectable ...

Package Information: Penicillin G Benzathine and Penicillin G Procaine is available in vials of 100 mL and 250 mL with each mL containing 150,000 units penicillin G benzathine and 150,000 units penicillin G procaine. Penicillin G Benzathine and Penicillin G Procaine should be stored under refrigeration 2°-8°C (36°-46°F). Avoid freezing.

Neurosyphilis Treatment Outcomes After Intravenous ...

We evaluated 150 people with CSF abnormalities who were treated with either intravenous aqueous penicillin G (PenG) or intramuscular aqueous procaine penicillin G plus oral probenecid (APPG-P). An abnormal CSF diagnosis was defined as a white blood cell (WBC) count >20/µL, a CSF protein reading >50 mg/dL, or a reactive CSF-Venereal Disease ...

Bicillin C-R (penicillin G benzathine and penicillin G ...

Penicillin G procaine, (2S,5R,6R)-3,3-Dimethyl-7-oxo-6-(2-phenylacetamido)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid compound with 2-(diethylamino)ethyl p-aminobenzoate (1:1) monohydrate, is an equimolar salt of procaine and penicillin G. It occurs as white crystals or a white, microcrystalline powder and is slightly soluble in water.

Penicillin G Procaine - Manufacturers, Suppliers & Dealers

Find listing of penicillin g procaine, penicillin g procaine manufacturers, suppliers, dealers & exporters from India. Get penicillin g procaine at best price from …

Penicillin G/Norocillin Injectable - PBS Animal Health

Indicated for the treatment of pneumonia and shipping fever in cattle and sheep, erysipelas in swine, and strangles in horses. Contains 300,000 units of penicillin G procaine per ml.Dosage: Cattle, sheep, swine and horses - 1 ml IM per 100 lbs body weight once daily. Continue treatment until recovery is apparent and for at least 1 day after symptoms disappear, usually in 2-3 days.

penicillin G benzathine/penicillin G procaine (Rx) - Medscape

Medscape - Streptococcal group A infection dosing for Bicillin C-R, Bicillin C-R 900/300 (penicillin G benzathine/penicillin G procaine), frequency-based adverse effects, comprehensive interactions, contraindications, pregnancy & lactation schedules, and cost information.

Goat-Link - Penicillin G Procaine

Jan 14, 2010 · PENICILLIN G PROCAINE INJECTABLE SUSPENSION 300,000 Units per mL FOR ANIMAL USE ONLY DESCRIPTION: Penicillin G Procaine Injectable Suspension is available in 100-mL, 250-mL and 500-mL multiple-dose vials. Each mL contains: penicillin G procaine 300,000 units, methylparaben 1.3 mg, propylparaben 0.2 mg, sodium citrate 10 mg, sodium carboxymethylcellulose …

gonorrhoea procaine penicillin plus probenecid*

penicillin G, dissolved in 8 ml of0-5% lidocaine to obviate pain, combined with one oral dose of 1-0 g ofprobenecid given i hr before injection (Lomholt &Berg, 1966; Olsen &Lomholt, 1969). In the Far East the failure rate of 28-6% following single injections of 2-4 mega-units of aqueous procaine penicillin was reduced to only 2%if 1 0 g of pro-

Penicillin G procaine | C29H40N4O7S | ChemSpider

Procaine penicillin e G hydrate. XH9450000. (2S,5R,6R)-3,3-Dime thyl-7-oxo-6- (2-phe nylacetamido)-4-thi a-1-azabicyclo (3.2. 0)heptane-2-carboxy lic acid compound w ith 2- (diethylamino )ethyl p-aminobenzo ate (1:1) monohydra te.

Benzathine Penicillin G and Procaine Penicillin G in ...

The disposition of penicillin G in piglets is described after intramuscular or subcutaneous injection of depot preparations. The piglets were injected with 33 000 IU/kg or 100 000 IU/kg benzathine + procaine penicillin G intramuscularly or subcutaneously, or 100 000 IU/kg procaine penicillin G intramuscularly or subcutaneously.

Why does Penicillin concentration is given in Units and ...

T max is 4 h (procaine IM). Penicillin G–sensitive is highly sensitive to microorganisms that are susceptible to the low and very prolonged serum levels common to this dose form in man.

Liquid Chromatography | HPLC Systems | KNAUER

Penicillin is a group of antibiotics which include penicillin G (intravenous use), penicillin V (use by mouth), procaine penicillin, and benzathine penicillin (intramuscular use). Penicillin antibiotics were among the first medications to be effective against many …

How to give a horse a shot of penicillin

How much penicillin do you give a horse? Animals treated with Penicillin G Procaine Injectable Suspension Alternate Method should show noticeable improvement within 36 to 48 hours. DOSAGE: The dosage for cattle, sheep, swine, and horses is 3000 units per pound of body weight, or 1.0 mL for each 100 pounds of bodyweight, once daily.

Penicillin G Potassium - an overview | ScienceDirect Topics

Penicillin G potassium is available in 5- to 20-million-unit vials. Penicillin G benzathine is available in 150,000 units/mL and is usually combined with 150,000 units/mL of procaine penicillin G suspension. Benzathine penicillin products are not recommended. Procaine penicillin G is available in 300,000-units/mL suspension.

CAS # 54-35-3, Procaine penicillin G, Procaine ...

chemBlink provides information about CAS # 54-35-3, Procaine penicillin G, Procaine benzylpenicillin, molecular formula: C16H18N2O4S.C13H20N2O2.

ANNEX I: LIST OF NAMES OF THE VETERINARY …

Procaine benzylpenicillin 150,000 IU/ml; Procaine hydrochloride 20 mg/ml Emdoka bvba J. Lijsenstraat 16 B-2321 Hoogstraten : Belgium Duplocilline L.A. Benzathine benzylpenicillin 150,000 IU/ml Procaine benzylpenicillin 150,000 IU/ml Intervet Belgium Ragheno Park, Dellingstraat 32/1 B …

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